Professor Stephen Todryk

Professor

Department: Applied Sciences

Stephen Todryk is Professor of Immunology within the Department of Applied Sciences.

Having received a BSc in Applied & Human Biology in Aston, Birmingham in 1989, Steve went on to work in an NHS Immunology lab in Oxford for two years. He then embarked on a PhD at Guys Hospital, London, studying immunity and vaccines against streptococci, which he completed in 1995. He carried out postdoctoral studies on cancer immunotherapy at the Cancer Research UK lab at the Hammersmith Hospital and at St George’s London, before setting up a group as a Principal Investigator at the University of Maynooth in Ireland in 2000. He relocated his lab to Trinity College Dublin where he was a Research Lecturer. He came back to the UK, to Oxford University, in 2004, to lead the study of human immunological aspects of malaria vaccine development with Adrian Hill.

Steve joined Northumbria University in 2007 as a Senior Lecturer, became Reader in 2010 and was awarded personal Chair of Immunology in 2012.

Steve has been a member of the British Society for Immunology (BSI) since 1990, and served on the BSI council and local committee. He is a committee member of the local branch of the Royal Society of Biology (RSB), where he is Fellow.

He is also on the Editorial Boards of the following international journals:

Immunology (Impact Factor 5.0)

PloS ONE (Impact Factor 2.7)

Scientific Reports (Impact Factor 4.0)

Frontiers in Immunology (impact factor 6.4)

Cells (impact factor 4.4)

Vaccines (impact factor 4.1)

Email Stephen

Research Themes and Scholarly Interests

immunology
Recent and current projects:

Anti-microbial immunity in the lung, in obstructive lung diseases

Allergic responses in the lung

Immune responses in Chronic Fatigue

Immune responses in Heart Disease and COVID-19

Key Publications

Please visit the Pure Research Information Portal for further information
How Reliable Are Predictions of CD8+ T Cell Epitope Recognition? Lessons for Cancer, Lehmann, A., Lehmann, P., Todryk, S. 17 Apr 2024, In: Onco
The Bisdioxopiperazine ICRF-193 Attenuates LPS-induced IL-1β Secretion by Macrophages, Brindle, A., Bainbridge, C., Kumar, M., Todryk, S., Padget, K. 1 Feb 2024, In: Inflammation
Tracking Circulating HLA-Specific IgG-Producing Memory B Cells with the B-Cell ImmunoSpot Assay, Kervella, D., Heidt, S., Fairchild, R., Todryk, S., Bestard, O. 19 Mar 2024, Handbook of ELISPOT, New York, Springer
Engineering Approaches for Cellular Therapeutics and Diagnostics, Torun, H., Agrawal, P., Markwell, C., Fu, Y., Todryk, S., Moschos, S. 6 Apr 2023, Emerging Drug Delivery and Biomedical Engineering Technologies , Boca Raton, US, Taylor & Francis
Next generation organoid engineering to replace animals in cancer drug testing, Hockney, S., Parker, J., Turner, J., Todd, X., Todryk, S., Ger Gieling, R., Hilgen, G., Camargo Madeira Simoes, D., Pal, D. 1 Jul 2023, In: Biochemical Pharmacology
Role of monocytes/macrophages in renin-angiotensin system-induced hypertension and end organ damage, Barhoumi, T., Todryk, S. 3 Oct 2023, In: Frontiers in Physiology
The Effect of Menstrual-Cycle Phase on Immune Responses to a 5-km Cycling Time Trial: An Exploratory Study, Hicks, K., Orange, S., Dulson, D., Ansdell, P., Todryk, S., Gilbert, S., Saxton, J. 1 Apr 2023, In: International Journal of Sports Physiology and Performance
Acute aerobic exercise‐conditioned serum reduces colon cancer cell proliferation in vitro through interleukin‐6‐induced regulation of DNA damage, Orange, S., Jordan, A., Odell, A., Kavanagh, O., Hicks, K., Eaglen, T., Todryk, S., Saxton, J. 15 Jul 2022, In: International Journal of Cancer
Reply to “Comments on: Acute aerobic exercise‐conditioned serum reduces colon cancer cell proliferation in vitro through interleukin‐6‐induced regulation of DNA damage”, Orange, S., Jordan, A., Odell, A., Kavanagh, O., Hicks, K., Todryk, S., Saxton, J. 1 Nov 2022, In: International Journal of Cancer
Revisiting the Elusive Hepatitis C Vaccine, Todryk, S., Bassendine, M., Bridge, S. 2 Feb 2021, In: Vaccines

Current and Recent Projects

Please visit the Pure Research Information Portal for further information
The role of maternal folate in childhood leukemia initiation; understanding the molecular mechanisms, McKay, J. (Principal Investigator), Todryk, S. (Co Investigator), World Cancer Research Fund International, 01/04/23 - 31/03/27, £346,625.00

PGR Supervision

Sajidah Hasan Immune Responses Against Foreign and Self-Antigens in Lung Diseases Start Date: 03/06/2013 End Date: 14/11/2017
Lucy Appleby Analysing the Potential Anti-Inflammatory Effects of Vitamin D on Human Corneal Epithelial Cells Start Date: 31/07/2020 End Date: 15/07/2022
Fathia Jaat Anti-Microbial Immune Profiles in Obstructive Lung Diseases Start Date: 01/02/2013 End Date: 10/11/2017
Adam Tabet Start Date: 01/03/2016
Santosh Murali Anti-Microbial Immune Responses, focusing on Herpes viruses, in Myocardial Infarction and Chronic Fatigue Syndrome Start Date: 02/04/2013 End Date: 16/09/2019
Georgia Stylianou Development, optimisation and characterization of memory B cell ELISPOT in infectious diseases and autoimmunity Start Date: 01/10/2023

Further Information

immunology

Qualifications

Biomedical Science PhD April 01 1996
Applied Biology BSc (Hons) July 14 1989
Associate Fellow of Higher Education Academy AFHEA 2021

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